ARA-290

Buy ARA-290 — Innate Repair Receptor Research Peptide

Researchers looking to buy ARA-290 for laboratory study will find this peptide a compound of specific interest in anti-inflammatory and tissue-protective research. ARA-290 (also known as Cibinetide) is a synthetic 11-amino-acid peptide derived from a region of the erythropoietin (EPO) molecule — specifically engineered to interact with the innate repair receptor (IRR) while lacking the erythropoietic (red blood cell-stimulating) activity of EPO itself. This separation of tissue-protective activity from hematopoietic activity is the defining feature of ARA-290 in research literature.

Mechanism of Action

ARA-290 has been investigated in published research for activity across several biological pathways, including:

• Innate repair receptor (IRR) agonism — the peptide targets the innate repair receptor, a heteromer complex studied in tissue-protective and anti-inflammatory research
• Anti-inflammatory signaling — research on cytokine modulation and inflammatory pathway suppression
• Neuropathic research — investigations into small nerve fiber pathways and neuropathic research models, one of ARA-290’s most-studied applications
• Tissue-protective research — studies on cellular protection under inflammatory and ischemic stress conditions, without erythropoietic effects
• Corneal nerve fiber research — documented research interest in small nerve fiber density and regeneration research models

The key distinction in ARA-290 research is that it engages the tissue-protective pathways associated with EPO while avoiding the red blood cell-stimulating effects — making it a research tool for investigating EPO’s protective mechanisms independent of its hematopoietic function.

Research Applications

ARA-290 is used in research contexts including:

• Innate repair receptor pharmacology research
• Anti-inflammatory and cytokine pathway research
• Neuropathic and small nerve fiber research models
• Tissue protection and cellular stress research
• Corneal nerve fiber research
• Comparative EPO-derivative research

Product Specifications

• Compound: ARA-290 (Cibinetide)
• Form: Lyophilized white powder
• Purity: ≥99% (verified by HPLC and mass spectrometry)
• Available sizes: 10mg
• Third-party tested: Certificate of Analysis available on request

Reconstitution & Storage

Lyophilized ARA-290 should be stored at -20°C for long-term stability and protected from light. Once reconstituted with bacteriostatic water, the solution should be refrigerated at 2–8°C and used within the timeframe indicated on the product COA. Avoid repeated freeze-thaw cycles, as they can degrade peptide integrity.

Reconstitution ratios depend on the specific research protocol being followed.

Shipping & Handling

All orders are shipped with temperature-controlled packaging to preserve peptide integrity. Domestic orders typically arrive within 2–4 business days. Tracking is provided on every order.

Important Disclaimer

This product is sold strictly for laboratory research and in-vitro use only. It is not intended for human or animal consumption, diagnostic use, therapeutic use, pain management, or any form of clinical or personal application. By purchasing, you confirm that you are a qualified researcher or affiliated with a licensed research institution and that this product will be handled in accordance with all applicable laws and safety standards.

ARA-290 has not completed human clinical approval and is not approved by the FDA for any use.