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SS-31

(317 customer reviews)

$65.00

Buy SS-31 (Elamipretide) research peptide from Kinetic Compounds — synthetic mitochondrial-targeted tetrapeptide studied for cardiolipin binding, mitochondrial membrane stabilization, and ROS reduction in bioenergetics research. Lyophilized powder, ≥99% purity, third-party tested. For laboratory and research use only — not for human consumption.

Weight0.015 kg
Peptide Family
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Description

Buy SS-31 (Elamipretide) — Mitochondrial-Targeted Research Peptide

Researchers looking to buy SS-31 for laboratory study will find this synthetic mitochondrial-targeted tetrapeptide is one of the most extensively researched mitochondrial peptides in modern bioenergetics literature. SS-31 (also known as Elamipretide and Bendavia) was developed at Cornell University by Dr. Hazel Szeto and Dr. Peter Schiller — the “SS” prefix refers to the names of the developers. The compound belongs to the Szeto-Schiller (SS) peptide family of mitochondrial-targeted compounds and has a clinical research base spanning multiple investigational trials in cardiovascular, renal, and ophthalmologic research.

Mechanism of Action

SS-31 has been investigated in published research for activity across several biological pathways, including:

  • Cardiolipin binding — selective binding to cardiolipin, a phospholipid uniquely concentrated in the inner mitochondrial membrane
  • Mitochondrial membrane stabilization — research on preservation of inner mitochondrial membrane structure and cristae architecture
  • Electron transport chain efficiency — investigations into ETC complex assembly and electron flow through Complexes I–IV
  • Reactive oxygen species (ROS) reduction — research on mitochondrial ROS generation and oxidative stress modulation
  • ATP production — studies on cellular bioenergetics and ATP synthesis capacity in compromised mitochondria research models
  • Mitochondrial permeability transition pore (mPTP) — research on mPTP opening and mitochondrial-driven apoptosis pathways
  • Cytochrome c stabilization — investigations into cardiolipin-cytochrome c interactions in the electron transport chain

SS-31 is distinguished in mitochondrial research literature by its selective targeting mechanism — the peptide accumulates in the inner mitochondrial membrane through its affinity for cardiolipin, independently of mitochondrial membrane potential. This passive, potential-independent targeting allows SS-31 to localize to mitochondria even in cells where mitochondrial function is already compromised, which is a defining feature in research models of mitochondrial dysfunction.

Research Applications

SS-31 is widely used in research contexts including:

  • Mitochondrial dysfunction and bioenergetics research models
  • Cardiovascular research, particularly ischemia-reperfusion injury models
  • Renal and kidney function research
  • Heart failure and cardiac mitochondrial research
  • Aging and mitochondrial decline research
  • Neurodegenerative research models involving mitochondrial pathology
  • Skeletal muscle and exercise physiology research
  • Comparative analysis alongside other mitochondrial-active research compounds such as MOTS-c, NAD+, and Coenzyme Q10 analogs
  • Ophthalmologic research, including dry age-related macular degeneration models

Product Specifications

  • Compound: SS-31 (Elamipretide, Bendavia)
  • Sequence: D-Arg-Dmt-Lys-Phe-NH2
  • Form: Lyophilized white powder
  • Purity: ≥99% (verified by HPLC and mass spectrometry)
  • Available sizes: 10mg
  • Third-party tested: Certificate of Analysis available on request

Reconstitution & Storage

Lyophilized SS-31 should be stored at -20°C for long-term stability and protected from light. Once reconstituted with bacteriostatic water, the solution should be refrigerated at 2–8°C and used within the timeframe indicated on the product COA. Avoid repeated freeze-thaw cycles, as they can degrade peptide integrity.

Shipping & Handling

All orders are shipped with temperature-controlled packaging to preserve peptide integrity. Domestic orders typically arrive within 2–4 business days. Tracking is provided on every order.

Important Disclaimer

This product is sold strictly for laboratory research and in-vitro use only. It is not intended for human or animal consumption, diagnostic use, therapeutic use, or any form of clinical application. By purchasing, you confirm that you are a qualified researcher or affiliated with a licensed research institution and that this product will be handled in accordance with all applicable laws and safety standards.

SS-31 (Elamipretide) is an investigational compound that has been studied in human clinical trials but is not currently approved by the FDA for human use. This product is not a substitute for any prescribed medication.

Reviews (317)

317 reviews for SS-31

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Shipping & Delivery

Domestic Shipping (Canada)

We ship Canada-wide using Canada Post Xpresspost with full tracking provided on every shipment.

Standard delivery: 2-5 business days nationwide
Free shipping on orders over $200 CAD
Discreet, unmarked packaging on all orders
Tracking number provided via email upon dispatch

Storage & Handling

Storage & Handling

Proper storage and handling are essential to maintaining peptide stability and ensuring the integrity of your research material.

Storage Recommendations

Lyophilized peptides should be stored at -20°C for long-term preservation. For short-term storage of up to 30 days, refrigeration between 2-8°C is acceptable. Reconstituted peptides should always be refrigerated and used within 30 days.

Avoid the following:

Direct sunlight or UV exposure Repeated freeze-thaw cycles Temperature fluctuations Storage at room temperature beyond brief handling periods

Reconstitution Best Practices

Allow vials to reach room temperature before opening to prevent condensation. Use bacteriostatic water as the diluent for most peptides, injecting slowly along the side of the vial. Gently swirl to dissolve — do not shake. Allow the solution to fully dissolve before drawing for research use.

Shelf Life

Lyophilized peptides maintain potency for up to 24 months when stored properly at -20°C. Reconstituted solutions should be used within 30 days for optimal research results.

Research Disclaimer

Research Use Only

All products supplied by Kinetic Compounds are intended strictly for in-vitro laboratory research and development purposes.

Intended Use

These compounds are designed exclusively for qualified researchers and research institutions conducting laboratory studies. All products are research-grade and may not have been evaluated by the FDA for human use.

Prohibited Uses

Our products are NOT approved for:

Human consumption or administration Veterinary or animal use Diagnostic procedures Therapeutic applications Cosmetic application Resale for non-research purposes

Buyer Responsibility

By purchasing from Kinetic Compounds, you acknowledge and agree to the following:

You are a qualified researcher or represent a research institution All products will be used solely for in-vitro laboratory research You will handle products in accordance with applicable safety regulations You will not redistribute these compounds for human or animal consumption You assume full responsibility for the proper use and handling of these research materials